Poets | Bookstore | Poem of the Day | Top 40 | Search | Comments | Privacy
July 28th, 2014 - we have 234 poets, 8,025 poems and 115,441 comments.
Robert Frost - A Patch of Old Snow

There's a patch of old snow in a corner
That I should have guessed
Was a blow-away paper the rain
Had brought to rest.

It is speckled with grime as if
Small print overspread it,
The news of a day I've forgotten--
If I ever read it.

Share |

Added: Feb 1 2004 | Viewed: 1003 times | Comments and analysis of A Patch of Old Snow by Robert Frost Comments (12)

A Patch of Old Snow - Comments and Information

Poet: Robert Frost
Poem: 5. A Patch of Old Snow
Volume: Mountain Interval
Year: Published/Written in 1916

Comment 12 of 12, added on July 19th, 2014 at 1:20 AM.
WKjtXvsZWFddFJPV

wbZrT8 Thanks again for the blog.Really looking forward to read more. Will read on...

link building from Romania
Comment 11 of 12, added on May 25th, 2013 at 6:24 PM.
NASA Announces Brightest Lunar Explosion Ever Recorded wec

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread after receiving medical or surgical therapy to lower testosterone.

Prostate cancer forms in a gland in the male reproductive system found below the bladder and in front of the rectum. The male sex hormone testosterone stimulates the prostate tumors to grow. According to the National Cancer Institute, an estimated 238,590 men will be diagnosed with prostate cancer and 29,720 will die from the disease in 2013.

Xofigo is being approved more than three months ahead of the product¡¯s prescription drug user fee goal date of Aug. 14, 2013, the date the agency was scheduled to complete review of the drug application. The FDA reviewed Xofigo under the agency¡¯s priority review program, which provides for an expedited review of drugs that appear to provide safe and effective therapy when no satisfactory alternative therapy exists, or offer significant improvement compared to marketed products.

¡°Xofigo binds with minerals in the bone to deliver radiation directly to bone tumors, limiting the damage to the surrounding normal tissues,¡± said Richard Pazdur, M.D., director of the Office of Hematology and Oncology Products in the FDA¡¯s Center for Drug Evaluation and Research. ¡°Xofigo is the second prostate cancer drug approved by the FDA in the past year that demonstrates an ability to extend the survival of men with metastatic prostate cancer.¡±

In August 2012, the FDA approved Xtandi to treat men with metastatic castration-resistant prostate cancer that has spread or recurred, even with medical or surgical therapy to minimize testosterone. Xtandi is approved for patients who have previously been treated the chemotherapy drug docetaxel.

Xofigo¡¯s safety and effectiveness were evaluated in a single clinical trial of 809 men with symptomatic castration-resistant prostate cancer that spread to bones but not to other organs. Patients were randomly assigned to receive Xofigo or a placebo plus best standard of care.

The study was designed to measure overall survival. Results from a pre-planned interim analysis showed men receiving Xofigo lived a median of 14 months compared to a median of 11.2 months for men receiving placebo. An exploratory updated analysis conducted later in the trial confirmed Xofigo¡¯s ability to extend overall survival.

The most common side effects reported during clinical trials in men receiving Xofigo were nausea, diarrhea, vomiting and swelling of the leg, ankle or foot. The most common abnormalities detected during blood testing included low levels of red blood cells (anemia), lymphocytes (lymphocytopenia), white blood cells (leukopenia), platelets (thrombocytopenia) and infection-fighting white blood cells (neutropenia).
12312
12312

gandigoBligma from Hungary
Comment 10 of 12, added on April 20th, 2013 at 1:29 AM.
Where To Shop For The Perfect Pair Of Shoes For Playing Basketball

Youre so cool! I dont suppose Ive read anything like this prior to. So nice to get somebody with some original thoughts on this topic. realy thank you for beginning this up. this web site is something which is required on the internet, someone with a little originality. valuable job for bringing something new to the world wide web!




angesiaGela from Saudi Arabia

Are you looking for more information on this poem? Perhaps you are trying to analyze it? The poem, A Patch of Old Snow, has received 12 comments. Click here to read them, and perhaps post a comment of your own.

Poem Info

Frost Info
Copyright © 2000-2012 Gunnar Bengtsson. All Rights Reserved. Links | Bookstore