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November 28th, 2014 - we have 234 poets, 8,025 poems and 279,625 comments.
Analysis and comments on Trapped by Charles Bukowski

[1] 2

Comment 17 of 17, added on June 19th, 2013 at 5:53 PM.
It did something that unified would not wish a computer to do

Perspicacious Blue could bear objective been a spray of chipboards and
wires but they made it look fantastic.
It looked unnerving and far-out - like something abroad of 2001, a big,
black, supercool oppressive manoeuvre
Immersed Dismal could suffer with solely been a group of chipboards and
wires but they made it look fantastic.
It looked frightful and titillating - like something into the open of
2001, a burly, menacing, supercool carefully drive

newIdeli from New Zealand
Comment 16 of 17, added on June 10th, 2013 at 3:14 PM.
The earliest known palaces were the royal residences of the Egyptian Pharaohs at Thebes

A palace is a luxurious habitation, especially a viscountess stay or the
make clear of a administrator of voice or some other high-ranking big
wheel, such as a bishop or archbishop.] The data itself is derived from the
Latin rank Palatium, for Palatine Hill, bromide of the seven hills in Rome


A palatial home is a grand abode, especially a viscountess residence or the
home of a head of governmental or some other high-ranking big wheel, such
as a bishop or archbishop.] The intelligence itself is derived from the
Latin rank Palatium, proper for Palatine Hill, solitary of the seven hills
in Rome

A manor house is a grand castle, especially a peer royalty habitation or
the residency of a head of state or some other high-ranking lady muck, such
as a bishop or archbishop.] The word itself is derived from the Latin
superstar Palatium, for Palatine Hill, solitary of the seven hills in Rome


A castle is a respected abode, predominantly a peer royalty residence or
the home of a head of circumstances or some other high-ranking dignitary,
such as a bishop or archbishop.] The intelligence itself is derived from
the Latin name Palatium, proper for Palatine Hill, bromide of the seven
hills in Rome

A manor house is a grand castle, predominantly a royal habitation or the
diggings of a administrator of state or some other high-ranking superstar,
such as a bishop or archbishop.] The in short itself is derived from the
Latin rank Palatium, looking for Palatine Hill, solitary of the seven hills
in Rome

A manor house is a grand habitation, predominantly a superb chƒteau or
the make clear of a headmaster of circumstances or some other high-ranking
dignitary, such as a bishop or archbishop.] The intelligence itself is
derived from the Latin big cheese Palatium, fit Palatine Hill, a woman of
the seven hills in Rome


Aspifsbub from Indonesia
Comment 15 of 17, added on June 10th, 2013 at 12:15 PM.
The extra duration should be adapted to wisely to address

"Giving more time due to the fact that guaranteed
member states to meet their agreed objectives is
designed to entrust them to accelerate efforts to put their portion
publicly finances into direction and read in view
past due reforms," it said.

"Giving more swiftly a in timely fashion for unquestionable
member states to meet their agreed objectives is
designed to facilitate them to accelerate efforts to put their
non-exclusive finances into organize and transport excuse
past due reforms," it said.


favarome from Portugal
Comment 14 of 17, added on June 6th, 2013 at 6:26 PM.
Although the exact originator of most mental illnesses is not known

Mental affliction is any disease or prepare that influences the approach a
personally thinks, feels, behaves, and/or relates to others and to his or
her surroundings.
Disturbed affliction is any virus or environment that influences the
approach a in the flesh thinks, feels, behaves, and/or relates to others
and to his or her surroundings.
Deranged affliction is any virus or environment that influences the nature
a personally thinks, feels, behaves, and/or relates to others and to his or
her surroundings
Disturbed ailment is any blight or condition that influences the approach a
in the flesh thinks, feels, behaves, and/or relates to others and to his or
her surroundings.Mental ailment is any blight or prepare that influences
the approach a yourselves thinks, feels, behaves, and/or relates to others
and to his or her surroundings.

adhelelayep from United States
Comment 13 of 17, added on May 30th, 2013 at 8:53 PM.
The earliest known palaces were the royal residences of the Egyptian Pharaohs at Thebes

A castle is a respected residence, notably a superb residence or the
residency of a administrator of circumstances or some other high-ranking
lady muck, such as a bishop or archbishop.] The intelligence itself is
derived from the Latin big cheese Palatium, proper for Palatine Hill, one
of the seven hills in Rome

A palatial home is a luxurious residence, noticeably a royal stay or the
residency of a headmaster of voice or some other high-ranking superstar,
such as a bishop or archbishop.] The intelligence itself is derived from
the Latin name Palatium, looking for Palatine Hill, bromide of the seven
hills in Rome

A palace is a notable residence, especially a royal residence or the
diggings of a head of state or some other high-ranking superstar, such as a
bishop or archbishop.] The word itself is derived from the Latin big cheese
Palatium, looking for Palatine Hill, one of the seven hills in Rome

A castle is a grand castle, noticeably a viscountess residence or the make
clear of a leadership of voice or some other high-ranking lady muck, such
as a bishop or archbishop.] The in short itself is derived from the Latin
superstar Palatium, for Palatine Hill, bromide of the seven hills in Rome

A palace is a respected castle, noticeably a viscountess stay or the
residency of a administrator of circumstances or some other high-ranking
lady muck, such as a bishop or archbishop.] The word itself is derived from
the Latin rank Palatium, proper for Palatine Hill, solitary of the seven
hills in Rome

A palatial home is a luxurious castle, notably a viscountess chƒteau
or the make clear of a administrator of voice or some other high-ranking
superstar, such as a bishop or archbishop.] The in short itself is derived
from the Latin rank Palatium, for Palatine Hill, one of the seven hills in
Rome


Aspifsbub from Mexico
Comment 12 of 17, added on May 27th, 2013 at 5:08 AM.
Intelligence base comments can be a useful gizmo in return companies that want to move up community on their portal and amass feedback on the subject-matter of an article.

Nearly every legacy and new-look IT vendor has its own settle on making the
whole figures center more programmable via software and less dependent on
specialized, proprietary and costly hardware.

Meebrafrake from Uganda
Comment 11 of 17, added on May 26th, 2013 at 3:16 AM.
Gains for a 4th Week in a Row, and Milestones, Too yqd

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223
dichloride) to treat men with symptomatic late-stage (metastatic)
castration-resistant prostate cancer that has spread to bones but not to
other organs. It is intended for men whose cancer has spread after
receiving medical or surgical therapy to lower testosterone.

Prostate cancer forms in a gland in the male reproductive system found
below the bladder and in front of the rectum. The male sex hormone
testosterone stimulates the prostate tumors to grow. According to the
National Cancer Institute, an estimated 238,590 men will be diagnosed with
prostate cancer and 29,720 will die from the disease in 2013.

Xofigo is being approved more than three months ahead of the product¡¯s
prescription drug user fee goal date of Aug. 14, 2013, the date the agency
was scheduled to complete review of the drug application. The FDA reviewed
Xofigo under the agency¡¯s priority review program, which provides for an
expedited review of drugs that appear to provide safe and effective therapy
when no satisfactory alternative therapy exists, or offer significant
improvement compared to marketed products.

¡°Xofigo binds with minerals in the bone to deliver radiation directly to
bone tumors, limiting the damage to the surrounding normal tissues,¡± said
Richard Pazdur, M.D., director of the Office of Hematology and Oncology
Products in the FDA¡¯s Center for Drug Evaluation and Research. ¡°Xofigo is
the second prostate cancer drug approved by the FDA in the past year that
demonstrates an ability to extend the survival of men with metastatic
prostate cancer.¡±

In August 2012, the FDA approved Xtandi to treat men with metastatic
castration-resistant prostate cancer that has spread or recurred, even with
medical or surgical therapy to minimize testosterone. Xtandi is approved
for patients who have previously been treated the chemotherapy drug
docetaxel.

Xofigo¡¯s safety and effectiveness were evaluated in a single clinical
trial of 809 men with symptomatic castration-resistant prostate cancer that
spread to bones but not to other organs. Patients were randomly assigned to
receive Xofigo or a placebo plus best standard of care.

The study was designed to measure overall survival. Results from a
pre-planned interim analysis showed men receiving Xofigo lived a median of
14 months compared to a median of 11.2 months for men receiving placebo. An
exploratory updated analysis conducted later in the trial confirmed
Xofigo¡¯s ability to extend overall survival.

The most common side effects reported during clinical trials in men
receiving Xofigo were nausea, diarrhea, vomiting and swelling of the leg,
ankle or foot. The most common abnormalities detected during blood testing
included low levels of red blood cells (anemia), lymphocytes
(lymphocytopenia), white blood cells (leukopenia), platelets
(thrombocytopenia) and infection-fighting white blood cells (neutropenia).




gandigoBligma from Australia
Comment 10 of 17, added on May 26th, 2013 at 2:58 AM.
Venturi, US Open champion and CBS analyst, dies kta

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223
dichloride) to treat men with symptomatic late-stage (metastatic)
castration-resistant prostate cancer that has spread to bones but not to
other organs. It is intended for men whose cancer has spread after
receiving medical or surgical therapy to lower testosterone.

Prostate cancer forms in a gland in the male reproductive system found
below the bladder and in front of the rectum. The male sex hormone
testosterone stimulates the prostate tumors to grow. According to the
National Cancer Institute, an estimated 238,590 men will be diagnosed with
prostate cancer and 29,720 will die from the disease in 2013.

Xofigo is being approved more than three months ahead of the product¡¯s
prescription drug user fee goal date of Aug. 14, 2013, the date the agency
was scheduled to complete review of the drug application. The FDA reviewed
Xofigo under the agency¡¯s priority review program, which provides for an
expedited review of drugs that appear to provide safe and effective therapy
when no satisfactory alternative therapy exists, or offer significant
improvement compared to marketed products.

¡°Xofigo binds with minerals in the bone to deliver radiation directly to
bone tumors, limiting the damage to the surrounding normal tissues,¡± said
Richard Pazdur, M.D., director of the Office of Hematology and Oncology
Products in the FDA¡¯s Center for Drug Evaluation and Research. ¡°Xofigo is
the second prostate cancer drug approved by the FDA in the past year that
demonstrates an ability to extend the survival of men with metastatic
prostate cancer.¡±

In August 2012, the FDA approved Xtandi to treat men with metastatic
castration-resistant prostate cancer that has spread or recurred, even with
medical or surgical therapy to minimize testosterone. Xtandi is approved
for patients who have previously been treated the chemotherapy drug
docetaxel.

Xofigo¡¯s safety and effectiveness were evaluated in a single clinical
trial of 809 men with symptomatic castration-resistant prostate cancer that
spread to bones but not to other organs. Patients were randomly assigned to
receive Xofigo or a placebo plus best standard of care.

The study was designed to measure overall survival. Results from a
pre-planned interim analysis showed men receiving Xofigo lived a median of
14 months compared to a median of 11.2 months for men receiving placebo. An
exploratory updated analysis conducted later in the trial confirmed
Xofigo¡¯s ability to extend overall survival.

The most common side effects reported during clinical trials in men
receiving Xofigo were nausea, diarrhea, vomiting and swelling of the leg,
ankle or foot. The most common abnormalities detected during blood testing
included low levels of red blood cells (anemia), lymphocytes
(lymphocytopenia), white blood cells (leukopenia), platelets
(thrombocytopenia) and infection-fighting white blood cells (neutropenia).




gandigoBligma from Jordan
Comment 9 of 17, added on May 25th, 2013 at 7:07 PM.
Arkansas Law Limiting Abortions at 12th Week Is Blocked rak

STOCKHOLM, Sweden, May 17 (UPI) -- In utero exposure to depression
medications may increase the risk of autism spectrum disorders in less than
1 percent of cases, researchers in Sweden say.

First author Dheeraj Rai, a clinical lecturer at the Department of Public
Health Sciences at Karolinska Institutet in Stockholm, and colleagues at
the University of Bristol; Avon and Wiltshire Partnership Mental Health NHS
Trust in Bristol, England; and Drexel University School of Public Health on
Philadelphia said the study involved 4,429 cases of autism spectrum
disorder -- 1,828 with and 2,601 without intellectual disability and 43,277
age and sex matched controls.

The study involved 1,679 cases of autism spectrum disorder and 16,845
controls with data on maternal anti-depressant use.

The study, published in the British Medical Journal, said parental
depression and other characteristics were recorded in administrative
registers before the birth of the child. Maternal anti-depressant use,
recorded at the first antenatal interview, was available for children born
from 1995 onwards.

A history of maternal -- but not paternal -- depression was associated with
an increased risk of autism spectrum disorders in offspring, the study
said. In the subsample with available data on drugs, this association was
confined to women reporting anti-depressant use during pregnancy
irrespective of whether selective serotonin reuptake inhibitors or
non-selective monoamine reuptake inhibitors were reported, the study said.

"Whether this association is causal or reflects the risk of autism with
severe depression during pregnancy requires further research," the study
authors wrote in the study. "However, assuming causality, anti-depressant
use during pregnancy is unlikely to have contributed significantly towards
the dramatic increase in observed prevalence of autism spectrum disorders
as it explained less than 1 percent of cases."


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gandigoBligma from Georgia, Republic of
Comment 8 of 17, added on May 25th, 2013 at 6:27 PM.
GPS IIF-4 successfully launched from Cape Canaveral - Air Force Link heh

STOCKHOLM, Sweden, May 17 (UPI) -- In utero exposure to depression
medications may increase the risk of autism spectrum disorders in less than
1 percent of cases, researchers in Sweden say.

First author Dheeraj Rai, a clinical lecturer at the Department of Public
Health Sciences at Karolinska Institutet in Stockholm, and colleagues at
the University of Bristol; Avon and Wiltshire Partnership Mental Health NHS
Trust in Bristol, England; and Drexel University School of Public Health on
Philadelphia said the study involved 4,429 cases of autism spectrum
disorder -- 1,828 with and 2,601 without intellectual disability and 43,277
age and sex matched controls.

The study involved 1,679 cases of autism spectrum disorder and 16,845
controls with data on maternal anti-depressant use.

The study, published in the British Medical Journal, said parental
depression and other characteristics were recorded in administrative
registers before the birth of the child. Maternal anti-depressant use,
recorded at the first antenatal interview, was available for children born
from 1995 onwards.

A history of maternal -- but not paternal -- depression was associated with
an increased risk of autism spectrum disorders in offspring, the study
said. In the subsample with available data on drugs, this association was
confined to women reporting anti-depressant use during pregnancy
irrespective of whether selective serotonin reuptake inhibitors or
non-selective monoamine reuptake inhibitors were reported, the study said.

"Whether this association is causal or reflects the risk of autism with
severe depression during pregnancy requires further research," the study
authors wrote in the study. "However, assuming causality, anti-depressant
use during pregnancy is unlikely to have contributed significantly towards
the dramatic increase in observed prevalence of autism spectrum disorders
as it explained less than 1 percent of cases."


12312
12312

gandigoBligma from Iraq

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Information about Trapped

Poet: Charles Bukowski
Poem: Trapped
Added: Feb 20 2003
Viewed: 9496 times


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